Dr Ryan Stone, an engineer on her first space mission, and Matt Kowalski, an astronaut on his final expedition, have to survive in space after they are hit by debris while spacewalking.
Robert Neville is a scientist who was unable to stop the spread of the terrible virus that was incurable and man-made. Immune, Neville is now the last human survivor in what is left of New York City and perhaps the world. For three years, Neville has faithfully sent out daily radio messages, desperate to find any other survivors who might be out there. But he is not alone.
Following the events at home, the Abbott family now face the terrors of the outside world. Forced to venture into the unknown, they realize that the creatures that hunt by sound are not the only threats that lurk beyond the sand path.